Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 3.958


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
Hoxa6 15403 homeobox A6
Hoxa7 15404 homeobox A7
Hoxb6 15414 homeobox B6
Hoxb7 15415 homeobox B7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxa7chr6_-_521685710.083.1e-01Click!
Hoxb6chr11_+_96160484-0.018.7e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_56040211 224.941 Gpm6a
glycoprotein m6a
chr8_+_56040445 216.821 Gpm6a
glycoprotein m6a
chr8_+_56040553 199.388 Gpm6a
glycoprotein m6a
chr8_+_56040080 187.589 NM_153581
Gpm6a
glycoprotein m6a
chr8_+_56040193 183.387 Gpm6a
glycoprotein m6a
chr13_+_42776161 131.633 Phactr1
phosphatase and actin regulator 1
chr3_+_68376319 111.527 Schip1
schwannomin interacting protein 1
chr10_+_69487700 110.800 Ank3
ankyrin 3, epithelial
chr17_-_90487479 109.531 Nrxn1
neurexin I
chr16_+_7069971 108.774 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_30000031 101.099 Spnb2
spectrin beta 2
chr3_+_67696141 100.219 NM_001113419
NM_177585
Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr3_+_17695743 99.031 6430547I21Rik
RIKEN cDNA 6430547I21 gene
chrX_+_10173557 98.994


chr13_+_42775991 98.417 NM_198419
Phactr1
phosphatase and actin regulator 1
chr9_-_91255831 95.085 Zic1
zinc finger protein of the cerebellum 1
chrX_+_54032914 93.826 Fhl1
four and a half LIM domains 1
chrX_+_132424640 93.624 Bhlhb9
basic helix-loop-helix domain containing, class B9
chr14_+_28689289 93.342 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr16_+_7069927 92.902 NM_183188
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_-_94287950 90.768 NM_001081377
Pcdh9
protocadherin 9
chrX_+_54032858 89.546 NM_001077362
Fhl1
four and a half LIM domains 1
chrX_-_100381973 84.547 NM_008671
Nap1l2
nucleosome assembly protein 1-like 2
chr3_+_68376289 84.224 NM_013928
Schip1
schwannomin interacting protein 1
chr12_+_30219769 83.152 NM_001093776
Myt1l
myelin transcription factor 1-like
chrX_-_100381703 82.399 Nap1l2
nucleosome assembly protein 1-like 2
chr10_+_40657980 81.523 Wasf1
WASP family 1
chr15_+_91991704 79.535 NM_001159647
Cntn1
contactin 1
chr5_-_122907002 78.475 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr15_-_90764873 77.834 Kif21a
kinesin family member 21A
chr4_+_101180625 76.079 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_13946371 75.925 NM_001163329
NM_001163330
Ralyl

RALY RNA binding protein-like

chr10_-_31410391 74.916 Nkain2
Na+/K+ transporting ATPase interacting 2
chr10_+_90038471 73.930 NM_001177397
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_-_25637786 72.173 Celf4
CUGBP, Elav-like family member 4
chr5_-_122906470 70.216 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr16_-_42340613 69.944 NM_008083
Gap43
growth associated protein 43
chr1_-_79436564 69.934 NM_009129
Scg2
secretogranin II
chr11_-_41814008 69.550 NM_008073
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr18_+_82754829 69.413 Mbp
myelin basic protein
chr9_-_112090150 69.136 NM_033264
NM_001177615
NM_001177620
NM_028755
Arpp21



cyclic AMP-regulated phosphoprotein, 21



chr4_+_138012860 68.754 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr8_+_56122680 68.584 Gpm6a
glycoprotein m6a
chr6_-_13785233 67.377 Gpr85
G protein-coupled receptor 85
chr14_-_109313298 67.326 Slitrk1
SLIT and NTRK-like family, member 1
chr18_-_42900793 66.988 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_+_82754586 66.914 Mbp
myelin basic protein
chr18_-_25637339 66.843 Celf4
CUGBP, Elav-like family member 4
chr18_-_12914177 66.785 Osbpl1a
oxysterol binding protein-like 1A
chr12_+_110782654 66.178 Meg3
maternally expressed 3
chr14_-_109313333 66.136 Slitrk1
SLIT and NTRK-like family, member 1
chr15_+_18750083 65.941 NM_009865
Cdh10
cadherin 10
chr2_-_140485267 65.631 Flrt3
fibronectin leucine rich transmembrane protein 3
chr16_-_84955086 65.225 App
amyloid beta (A4) precursor protein
chr9_-_29770699 64.138 NM_172290
Ntm
neurotrimin
chr18_+_82754377 63.367 Mbp
myelin basic protein
chr11_-_41813792 62.914 NM_177408
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr1_-_170085342 61.043 Pbx1
pre B-cell leukemia transcription factor 1
chr19_+_23241546 60.918 Klf9
Kruppel-like factor 9
chr6_-_13789847 57.884 NM_145066
Gpr85
G protein-coupled receptor 85
chr5_+_19413335 55.774 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr5_-_49280703 55.494 NM_030265
Kcnip4
Kv channel interacting protein 4
chr1_+_66368571 55.194 Mtap2
microtubule-associated protein 2
chr3_+_17954324 55.179 NM_021560
Bhlhe22
basic helix-loop-helix family, member e22
chr8_-_55804030 54.413 NM_028220
Wdr17
WD repeat domain 17
chr9_-_55983967 54.122 Tspan3
tetraspanin 3
chr4_-_109960078 53.727 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_8509479 52.999 NM_025285
Stmn2
stathmin-like 2
chr1_-_166368439 52.287 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr14_+_14286471 51.612 NM_001163032
Synpr
synaptoporin
chr3_-_83967952 51.612 Trim2
tripartite motif-containing 2
chr5_-_51848420 51.347 Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr3_-_63654912 51.239 NM_001177732
NM_001177733
NM_183191
Plch1


phospholipase C, eta 1


chr15_-_8660729 50.205 NM_148938
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_37389073 49.865 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chrX_-_40627962 49.733 NM_011855
Odz1
odd Oz/ten-m homolog 1 (Drosophila)
chr2_-_57905140 49.514 NM_029972
Ermn
ermin, ERM-like protein
chr15_-_44584003 49.244 NM_178765
Sybu
syntabulin (syntaxin-interacting)
chr11_-_97372344 49.095 Srcin1
SRC kinase signaling inhibitor 1
chr8_-_47292973 49.073 Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr3_+_114783882 47.505 NM_153157
Olfm3
olfactomedin 3
chr12_+_118997623 47.424 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr19_+_38339167 47.292 NM_020278
Lgi1
leucine-rich repeat LGI family, member 1
chr3_+_55265654 47.085 NM_001111051
NM_001111052
NM_001195539
NM_001195540
Dclk1



doublecortin-like kinase 1



chr5_+_67067359 47.073 NM_011670
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr16_+_7409879 46.789 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr9_+_31923720 46.289 NM_001195632
Arhgap32
Rho GTPase activating protein 32
chr16_+_92086695 45.808 Slc5a3
solute carrier family 5 (inositol transporters), member 3
chr17_+_70871444 45.743 NM_001128180
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr18_-_31606908 45.614 NM_009308
Syt4
synaptotagmin IV
chrX_+_102318792 45.508 Magee1
melanoma antigen, family E, 1
chr10_+_4978808 45.118 Syne1
synaptic nuclear envelope 1
chr2_+_109532592 44.907 NM_001048141
Bdnf
brain derived neurotrophic factor
chr6_-_92431385 44.892 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr12_+_110834872 44.876 1110006E14Rik
RIKEN cDNA 1110006E14 gene
chr8_+_115093942 44.675 NM_130457
Cntnap4
contactin associated protein-like 4
chr18_+_37925619 44.507 Pcdhga12
protocadherin gamma subfamily A, 12
chr2_+_138104219 44.489 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr19_-_37250472 44.480 Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr12_+_110800212 44.472 Meg3
maternally expressed 3
chr12_+_91570569 44.273 Nrxn3
neurexin III
chrX_+_139997806 44.053 NM_008778
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_-_76240202 43.897 NM_011211
Ptprd
protein tyrosine phosphatase, receptor type, D
chr2_+_61884596 43.868 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr12_+_30213224 43.364 NM_001093775
NM_001093778
NM_008666
Myt1l


myelin transcription factor 1-like


chr8_-_87297283 42.928 Nfix
nuclear factor I/X
chr4_-_91066674 42.600 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr12_+_39510297 42.545 NM_001163154
Etv1
ets variant gene 1
chr15_+_81626455 42.536 Zc3h7b
zinc finger CCCH type containing 7B
chr8_-_47292863 42.465


chr7_+_107422781 42.369 Pgm2l1
phosphoglucomutase 2-like 1
chr17_+_70871393 42.327 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr16_+_43247396 42.295 NM_019778
NM_181058
Zbtb20

zinc finger and BTB domain containing 20

chr16_-_84955488 42.156 App
amyloid beta (A4) precursor protein
chr3_+_55265811 42.113 Dclk1
doublecortin-like kinase 1
chrX_+_155897136 41.985 Mtap7d2
MAP7 domain containing 2
chr15_-_8660479 41.494 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_+_98486068 41.173 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr14_+_13073221 41.092 Ptprg
protein tyrosine phosphatase, receptor type, G
chr13_+_59234737 40.272 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr4_-_109959185 40.114 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_-_116782524 40.051 Cpsf6
cleavage and polyadenylation specific factor 6
chr17_-_85461840 40.038 Prepl
prolyl endopeptidase-like
chr3_-_122241909 39.970 Fnbp1l
formin binding protein 1-like
chr3_+_136598184 39.949 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr10_+_69488049 39.798 Ank3
ankyrin 3, epithelial
chr11_-_73137838 39.775 Aspa
aspartoacylase
chr8_-_67071497 39.730


chr3_+_136598485 39.349 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr9_-_83003967 39.212


chr5_-_122907269 39.021 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_59192308 38.951 Pkp4
plakophilin 4
chr1_-_42749940 38.885 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr18_+_37834003 38.825 Pcdhga3
protocadherin gamma subfamily A, 3
chr11_-_79317471 38.586 Omg
oligodendrocyte myelin glycoprotein
chr14_-_109313447 38.554 NM_199065
Slitrk1
SLIT and NTRK-like family, member 1
chr11_-_79317583 38.026 NM_019409
Omg
oligodendrocyte myelin glycoprotein
chr9_+_75159201 38.025 NM_010313
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr3_-_126701367 37.738 NM_178655
Ank2
ankyrin 2, brain
chr9_-_112134930 37.506 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr12_+_110783786 37.390 Meg3
maternally expressed 3
chr13_+_42961598 37.377 Phactr1
phosphatase and actin regulator 1
chr10_+_4978047 37.134 Syne1
synaptic nuclear envelope 1
chr9_-_112134984 36.982 NM_001177616
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr15_-_8660462 36.980 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_69648350 36.899 NM_198862
Nlgn2
neuroligin 2
chr2_+_97307652 36.799 NM_178725
Lrrc4c
leucine rich repeat containing 4C
chr11_+_117623703 36.748 Tnrc6c
trinucleotide repeat containing 6C
chr15_-_8660442 36.743 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_57810230 36.635 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr19_+_10525829 36.561


chr17_+_71168939 36.144 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_77357674 35.566 NM_001113400
Zfp385b
zinc finger protein 385B
chr18_+_57628139 35.280 NM_001134697
Ctxn3
cortexin 3
chr7_+_107789414 35.051 Rab6
RAB6, member RAS oncogene family
chr1_-_134603848 34.976 NM_001160318
Nfasc
neurofascin
chr18_+_38476622 34.631


chr18_+_82753560 34.524 Mbp
myelin basic protein
chr10_-_63552994 34.335 NM_178678
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chrX_+_162782484 34.081 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr2_+_174171943 34.077


chr11_+_87032504 33.998 Trim37
tripartite motif-containing 37
chr14_+_120830603 33.876 Mbnl2
muscleblind-like 2
chr4_+_101180580 33.648 NM_001164584
NM_001164585
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr1_+_34364633 33.452 Dst
dystonin
chr2_-_79969095 33.383 NM_016744
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr17_-_90436488 33.264 Nrxn1
neurexin I
chr17_+_17539832 33.248 Lix1
limb expression 1 homolog (chicken)
chr12_-_32398730 33.163 NM_175191
Gpr22
G protein-coupled receptor 22
chr5_+_67067497 33.128 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr8_-_70342105 32.949 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr3_+_55586431 32.728 NM_010750
Mab21l1
mab-21-like 1 (C. elegans)
chr5_+_67067477 32.490 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr18_+_37821598 32.301 NM_033584
Pcdhga1
protocadherin gamma subfamily A, 1
chr17_+_17539908 32.140 Lix1
limb expression 1 homolog (chicken)
chr1_-_170085798 32.112 Pbx1
pre B-cell leukemia transcription factor 1
chr4_-_86873866 31.884 NM_001110240
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr19_-_7500486 31.855


chr18_+_23573939 31.819 Dtna
dystrobrevin alpha
chr7_+_134094045 31.528 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr14_+_55506625 31.495 Bcl2l2
BCL2-like 2
chr1_-_194677940 31.435 NM_001177794
Sertad4
SERTA domain containing 4
chr12_-_42212538 31.327 Lrrn3
leucine rich repeat protein 3, neuronal
chrM_+_11741 31.029 ND5
NADH dehydrogenase subunit 5
chr2_-_77541328 30.985 NM_001113399
Zfp385b
zinc finger protein 385B
chr5_-_23012407 30.752 Srpk2
serine/arginine-rich protein specific kinase 2
chrX_+_140100287 30.689 NM_001195049
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr2_-_115890747 30.681 NM_001136072
NM_001159567
NM_001159568
NM_010825
Meis2



Meis homeobox 2



chrX_+_38754568 30.590 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_+_52202137 30.291 Vdac1
voltage-dependent anion channel 1
chr11_-_41996141 30.127 NM_010250
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chrX_-_22797942 30.049 Klhl13
kelch-like 13 (Drosophila)
chr8_-_37631532 29.767 Dlc1
deleted in liver cancer 1
chr3_-_146432922 29.673 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr11_+_42234760 29.647 Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr10_+_90039435 29.586 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chr11_-_41995688 29.510 Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr18_+_23573977 29.173 Dtna
dystrobrevin alpha
chr4_-_109959366 29.122 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr14_-_104213981 29.075



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.41 6.37e-20 GO:0032502 developmental process
1.42 1.31e-18 GO:0007275 multicellular organismal development
1.44 7.24e-18 GO:0048856 anatomical structure development
1.46 1.44e-17 GO:0048731 system development
1.59 3.56e-12 GO:0007399 nervous system development
1.53 9.11e-12 GO:0009653 anatomical structure morphogenesis
1.32 1.77e-11 GO:0051179 localization
1.73 1.86e-11 GO:0048699 generation of neurons
1.68 1.21e-10 GO:0022008 neurogenesis
1.78 1.86e-10 GO:0007155 cell adhesion
1.77 4.02e-10 GO:0022610 biological adhesion
1.33 1.40e-09 GO:0051234 establishment of localization
2.79 4.18e-09 GO:0007601 visual perception
2.79 4.18e-09 GO:0050953 sensory perception of light stimulus
1.32 6.60e-09 GO:0006810 transport
1.31 9.81e-09 GO:0048518 positive regulation of biological process
1.10 1.16e-08 GO:0009987 cellular process
1.78 1.51e-08 GO:0030182 neuron differentiation
1.32 2.47e-08 GO:0048522 positive regulation of cellular process
1.27 3.68e-08 GO:0060255 regulation of macromolecule metabolic process
1.24 5.94e-08 GO:0019222 regulation of metabolic process
1.37 6.32e-08 GO:0030154 cell differentiation
1.29 9.30e-08 GO:0016043 cellular component organization
1.17 1.48e-07 GO:0044238 primary metabolic process
1.38 1.70e-07 GO:0048513 organ development
1.35 1.98e-07 GO:0048869 cellular developmental process
1.57 2.02e-07 GO:0048468 cell development
1.83 2.36e-07 GO:0048666 neuron development
1.17 3.42e-07 GO:0044237 cellular metabolic process
1.24 4.81e-07 GO:0031323 regulation of cellular metabolic process
1.33 4.84e-07 GO:0071842 cellular component organization at cellular level
2.13 8.41e-07 GO:0001654 eye development
1.27 8.55e-07 GO:0071840 cellular component organization or biogenesis
1.24 9.38e-07 GO:0080090 regulation of primary metabolic process
1.53 1.19e-06 GO:2000026 regulation of multicellular organismal development
1.31 3.66e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.27 3.96e-06 GO:0010468 regulation of gene expression
1.89 5.06e-06 GO:0000904 cell morphogenesis involved in differentiation
1.47 5.47e-06 GO:0050793 regulation of developmental process
1.38 7.59e-06 GO:0051239 regulation of multicellular organismal process
2.65 8.30e-06 GO:0048592 eye morphogenesis
1.31 8.43e-06 GO:0048523 negative regulation of cellular process
1.73 1.07e-05 GO:0000902 cell morphogenesis
1.29 1.27e-05 GO:0048519 negative regulation of biological process
1.58 1.86e-05 GO:0007154 cell communication
4.07 1.89e-05 GO:0009583 detection of light stimulus
1.27 2.02e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.74 2.19e-05 GO:0060284 regulation of cell development
1.77 2.84e-05 GO:0051960 regulation of nervous system development
1.45 3.37e-05 GO:0051641 cellular localization
1.79 3.63e-05 GO:0007423 sensory organ development
1.51 3.88e-05 GO:0045595 regulation of cell differentiation
1.96 3.98e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.18 4.47e-05 GO:0044260 cellular macromolecule metabolic process
1.72 4.48e-05 GO:0007267 cell-cell signaling
1.25 4.84e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 5.49e-05 GO:0045664 regulation of neuron differentiation
1.13 6.27e-05 GO:0008152 metabolic process
1.79 7.46e-05 GO:0050767 regulation of neurogenesis
2.07 9.98e-05 GO:0043010 camera-type eye development
2.88 1.01e-04 GO:0051494 negative regulation of cytoskeleton organization
1.25 1.05e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.81 1.09e-04 GO:0048858 cell projection morphogenesis
1.77 1.19e-04 GO:0019226 transmission of nerve impulse
1.77 1.19e-04 GO:0035637 multicellular organismal signaling
1.63 1.26e-04 GO:0030030 cell projection organization
1.90 1.27e-04 GO:0048812 neuron projection morphogenesis
1.16 1.29e-04 GO:0043170 macromolecule metabolic process
4.25 1.31e-04 GO:0007602 phototransduction
3.19 1.38e-04 GO:0043244 regulation of protein complex disassembly
1.96 1.49e-04 GO:0007409 axonogenesis
1.26 1.93e-04 GO:0051252 regulation of RNA metabolic process
1.63 1.95e-04 GO:0032989 cellular component morphogenesis
1.24 1.98e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.37 2.02e-04 GO:0010604 positive regulation of macromolecule metabolic process
3.40 2.35e-04 GO:0043242 negative regulation of protein complex disassembly
1.26 2.39e-04 GO:0006355 regulation of transcription, DNA-dependent
1.86 2.65e-04 GO:0007268 synaptic transmission
1.78 2.80e-04 GO:0032990 cell part morphogenesis
1.75 3.85e-04 GO:0031175 neuron projection development
1.42 4.51e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.40 7.34e-04 GO:0032879 regulation of localization
1.23 7.35e-04 GO:0031326 regulation of cellular biosynthetic process
1.29 7.59e-04 GO:0065008 regulation of biological quality
1.44 9.37e-04 GO:0051649 establishment of localization in cell
1.33 1.03e-03 GO:0009893 positive regulation of metabolic process
1.51 1.21e-03 GO:0009887 organ morphogenesis
1.23 1.26e-03 GO:0010467 gene expression
1.44 1.41e-03 GO:0051128 regulation of cellular component organization
1.22 1.49e-03 GO:0009889 regulation of biosynthetic process
2.82 1.49e-03 GO:0009582 detection of abiotic stimulus
1.19 1.65e-03 GO:0034641 cellular nitrogen compound metabolic process
3.67 2.37e-03 GO:0042461 photoreceptor cell development
1.85 2.40e-03 GO:0051129 negative regulation of cellular component organization
3.83 2.45e-03 GO:0042462 eye photoreceptor cell development
1.31 2.97e-03 GO:0023051 regulation of signaling
3.32 3.28e-03 GO:0046530 photoreceptor cell differentiation
1.33 3.30e-03 GO:0031325 positive regulation of cellular metabolic process
1.20 3.37e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.42 3.85e-03 GO:0001754 eye photoreceptor cell differentiation
1.21 6.21e-03 GO:0019538 protein metabolic process
1.18 6.33e-03 GO:0006807 nitrogen compound metabolic process
1.39 6.56e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.40 8.53e-03 GO:0010628 positive regulation of gene expression
1.61 1.24e-02 GO:0006163 purine nucleotide metabolic process
1.75 1.39e-02 GO:0048514 blood vessel morphogenesis
4.30 1.69e-02 GO:0007026 negative regulation of microtubule depolymerization
2.52 1.77e-02 GO:0048593 camera-type eye morphogenesis
1.46 1.83e-02 GO:0016192 vesicle-mediated transport
1.37 2.26e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 2.29e-02 GO:0072358 cardiovascular system development
1.49 2.29e-02 GO:0072359 circulatory system development
1.45 2.73e-02 GO:0046907 intracellular transport
1.48 2.81e-02 GO:0051094 positive regulation of developmental process
1.22 2.87e-02 GO:0044267 cellular protein metabolic process
1.21 2.89e-02 GO:0016070 RNA metabolic process
1.35 3.56e-02 GO:0031328 positive regulation of cellular biosynthetic process
3.60 3.59e-02 GO:0031111 negative regulation of microtubule polymerization or depolymerization
4.06 3.75e-02 GO:0031114 regulation of microtubule depolymerization
1.84 3.89e-02 GO:0001525 angiogenesis
1.39 3.93e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.08 4.21e-02 GO:0010639 negative regulation of organelle organization
1.30 4.45e-02 GO:0009966 regulation of signal transduction
1.54 4.66e-02 GO:0072521 purine-containing compound metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.18 4.79e-26 GO:0005622 intracellular
1.18 3.23e-25 GO:0044424 intracellular part
1.18 8.61e-19 GO:0043226 organelle
1.18 9.21e-19 GO:0043229 intracellular organelle
1.34 4.61e-17 GO:0071944 cell periphery
1.67 4.66e-16 GO:0042995 cell projection
1.19 1.85e-15 GO:0005737 cytoplasm
1.33 3.36e-15 GO:0005886 plasma membrane
1.71 6.09e-15 GO:0005626 insoluble fraction
2.01 9.44e-15 GO:0045202 synapse
1.18 1.27e-14 GO:0043227 membrane-bounded organelle
1.18 1.51e-14 GO:0043231 intracellular membrane-bounded organelle
1.61 2.14e-14 GO:0000267 cell fraction
1.26 2.54e-14 GO:0005634 nucleus
1.69 2.32e-13 GO:0005624 membrane fraction
1.08 1.44e-12 GO:0005623 cell
1.08 1.44e-12 GO:0044464 cell part
1.81 2.99e-11 GO:0043005 neuron projection
1.31 9.05e-10 GO:0043234 protein complex
1.24 2.40e-09 GO:0044422 organelle part
1.27 4.00e-09 GO:0032991 macromolecular complex
1.24 5.65e-09 GO:0044446 intracellular organelle part
1.94 1.72e-08 GO:0044456 synapse part
1.65 7.79e-08 GO:0030054 cell junction
1.17 7.55e-07 GO:0044444 cytoplasmic part
1.90 8.74e-07 GO:0048471 perinuclear region of cytoplasm
1.83 1.16e-06 GO:0044297 cell body
1.33 1.23e-06 GO:0044459 plasma membrane part
1.46 4.77e-06 GO:0005794 Golgi apparatus
1.80 9.66e-06 GO:0043025 neuronal cell body
1.27 1.04e-05 GO:0043228 non-membrane-bounded organelle
1.27 1.04e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.89 1.08e-05 GO:0030424 axon
1.35 1.40e-05 GO:0005829 cytosol
1.69 1.54e-05 GO:0044463 cell projection part
2.25 2.07e-05 GO:0019717 synaptosome
1.34 3.17e-05 GO:0005856 cytoskeleton
1.51 3.90e-04 GO:0015630 microtubule cytoskeleton
1.40 4.19e-04 GO:0044430 cytoskeletal part
1.73 5.85e-04 GO:0030425 dendrite
1.94 1.86e-03 GO:0045211 postsynaptic membrane
1.70 5.00e-03 GO:0045177 apical part of cell
1.93 5.45e-03 GO:0005938 cell cortex
1.45 7.80e-03 GO:0031988 membrane-bounded vesicle
3.04 8.72e-03 GO:0030666 endocytic vesicle membrane
1.33 1.09e-02 GO:0044421 extracellular region part
1.37 1.20e-02 GO:0031982 vesicle
1.46 1.22e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.38 1.33e-02 GO:0031410 cytoplasmic vesicle
1.23 1.78e-02 GO:0044428 nuclear part
2.56 1.81e-02 GO:0030863 cortical cytoskeleton
1.25 2.02e-02 GO:0031981 nuclear lumen
1.87 2.09e-02 GO:0030136 clathrin-coated vesicle
1.23 2.22e-02 GO:0070013 intracellular organelle lumen
1.23 2.57e-02 GO:0043233 organelle lumen
1.23 2.93e-02 GO:0031974 membrane-enclosed lumen
2.46 3.41e-02 GO:0030665 clathrin coated vesicle membrane
1.54 3.47e-02 GO:0031012 extracellular matrix
3.00 3.51e-02 GO:0001750 photoreceptor outer segment

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.36 7.01e-33 GO:0005515 protein binding
1.20 2.32e-31 GO:0005488 binding
1.67 1.75e-06 GO:0005509 calcium ion binding
1.20 9.79e-05 GO:0046872 metal ion binding
1.20 1.01e-04 GO:0043167 ion binding
1.20 1.02e-04 GO:0043169 cation binding
1.38 2.25e-04 GO:0005215 transporter activity
1.54 5.48e-04 GO:0019904 protein domain specific binding
1.52 1.41e-03 GO:0008092 cytoskeletal protein binding
1.39 1.76e-03 GO:0022892 substrate-specific transporter activity
1.35 2.78e-03 GO:0005102 receptor binding
1.38 3.66e-03 GO:0022857 transmembrane transporter activity
1.38 3.85e-03 GO:0019899 enzyme binding
1.89 6.33e-03 GO:0008022 protein C-terminus binding
1.20 1.05e-02 GO:0003676 nucleic acid binding
1.37 1.91e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.57 2.13e-02 GO:0016563 transcription activator activity
2.05 2.48e-02 GO:0015276 ligand-gated ion channel activity
2.05 2.48e-02 GO:0022834 ligand-gated channel activity
1.26 3.04e-02 GO:0008270 zinc ion binding
1.20 3.37e-02 GO:0000166 nucleotide binding
1.97 4.95e-02 GO:0015631 tubulin binding