Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 3.958


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
Hoxa6 15403 homeobox A6
Hoxa7 15404 homeobox A7
Hoxb6 15414 homeobox B6
Hoxb7 15415 homeobox B7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxa7chr6_-_521685710.083.1e-01Click!
Hoxb6chr11_+_96160484-0.018.7e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_56040211 224.941 Gpm6a
glycoprotein m6a
chr8_+_56040445 216.821 Gpm6a
glycoprotein m6a
chr8_+_56040553 199.388 Gpm6a
glycoprotein m6a
chr8_+_56040080 187.589 NM_153581
 Gpm6a
glycoprotein m6a
chr8_+_56040193 183.387 Gpm6a
glycoprotein m6a
chr13_+_42776161 131.633 Phactr1
phosphatase and actin regulator 1
chr3_+_68376319 111.527 Schip1
schwannomin interacting protein 1
chr10_+_69487700 110.800 Ank3
ankyrin 3, epithelial
chr17_-_90487479 109.531 Nrxn1
neurexin I
chr16_+_7069971 108.774 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_30000031 101.099 Spnb2
spectrin beta 2
chr3_+_67696141 100.219 NM_001113419
NM_177585
 Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr3_+_17695743 99.031 6430547I21Rik
RIKEN cDNA 6430547I21 gene
chrX_+_10173557 98.994


chr13_+_42775991 98.417 NM_198419
 Phactr1
phosphatase and actin regulator 1
chr9_-_91255831 95.085 Zic1
zinc finger protein of the cerebellum 1
chrX_+_54032914 93.826 Fhl1
four and a half LIM domains 1
chrX_+_132424640 93.624 Bhlhb9
basic helix-loop-helix domain containing, class B9
chr14_+_28689289 93.342 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr16_+_7069927 92.902 NM_183188
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 124 entries
Enrichment   P-value GO Accession GO Term
4.30 1.69e-02 GO:0007026 negative regulation of microtubule depolymerization
4.25 1.31e-04 GO:0007602 phototransduction
4.07 1.89e-05 GO:0009583 detection of light stimulus
4.06 3.75e-02 GO:0031114 regulation of microtubule depolymerization
3.83 2.45e-03 GO:0042462 eye photoreceptor cell development
3.67 2.37e-03 GO:0042461 photoreceptor cell development
3.60 3.59e-02 GO:0031111 negative regulation of microtubule polymerization or depolymerization
3.42 3.85e-03 GO:0001754 eye photoreceptor cell differentiation
3.40 2.35e-04 GO:0043242 negative regulation of protein complex disassembly
3.32 3.28e-03 GO:0046530 photoreceptor cell differentiation
3.19 1.38e-04 GO:0043244 regulation of protein complex disassembly
2.88 1.01e-04 GO:0051494 negative regulation of cytoskeleton organization
2.82 1.49e-03 GO:0009582 detection of abiotic stimulus
2.79 4.18e-09 GO:0007601 visual perception
2.79 4.18e-09 GO:0050953 sensory perception of light stimulus
2.65 8.30e-06 GO:0048592 eye morphogenesis
2.52 1.77e-02 GO:0048593 camera-type eye morphogenesis
2.13 8.41e-07 GO:0001654 eye development
2.08 4.21e-02 GO:0010639 negative regulation of organelle organization
2.07 9.98e-05 GO:0043010 camera-type eye development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 59 entries
Enrichment   P-value GO Accession GO Term
3.04 8.72e-03 GO:0030666 endocytic vesicle membrane
3.00 3.51e-02 GO:0001750 photoreceptor outer segment
2.56 1.81e-02 GO:0030863 cortical cytoskeleton
2.46 3.41e-02 GO:0030665 clathrin coated vesicle membrane
2.25 2.07e-05 GO:0019717 synaptosome
2.01 9.44e-15 GO:0045202 synapse
1.94 1.72e-08 GO:0044456 synapse part
1.94 1.86e-03 GO:0045211 postsynaptic membrane
1.93 5.45e-03 GO:0005938 cell cortex
1.90 8.74e-07 GO:0048471 perinuclear region of cytoplasm
1.89 1.08e-05 GO:0030424 axon
1.87 2.09e-02 GO:0030136 clathrin-coated vesicle
1.83 1.16e-06 GO:0044297 cell body
1.81 2.99e-11 GO:0043005 neuron projection
1.80 9.66e-06 GO:0043025 neuronal cell body
1.73 5.85e-04 GO:0030425 dendrite
1.71 6.09e-15 GO:0005626 insoluble fraction
1.70 5.00e-03 GO:0045177 apical part of cell
1.69 2.32e-13 GO:0005624 membrane fraction
1.69 1.54e-05 GO:0044463 cell projection part

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
2.05 2.48e-02 GO:0015276 ligand-gated ion channel activity
2.05 2.48e-02 GO:0022834 ligand-gated channel activity
1.97 4.95e-02 GO:0015631 tubulin binding
1.89 6.33e-03 GO:0008022 protein C-terminus binding
1.67 1.75e-06 GO:0005509 calcium ion binding
1.57 2.13e-02 GO:0016563 transcription activator activity
1.54 5.48e-04 GO:0019904 protein domain specific binding
1.52 1.41e-03 GO:0008092 cytoskeletal protein binding
1.39 1.76e-03 GO:0022892 substrate-specific transporter activity
1.38 2.25e-04 GO:0005215 transporter activity
1.38 3.66e-03 GO:0022857 transmembrane transporter activity
1.38 3.85e-03 GO:0019899 enzyme binding
1.37 1.91e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.36 7.01e-33 GO:0005515 protein binding
1.35 2.78e-03 GO:0005102 receptor binding
1.26 3.04e-02 GO:0008270 zinc ion binding
1.20 2.32e-31 GO:0005488 binding
1.20 9.79e-05 GO:0046872 metal ion binding
1.20 1.01e-04 GO:0043167 ion binding
1.20 1.02e-04 GO:0043169 cation binding